The hospital called DH to pick up the report and pay off the bill. I hope this is our last bill with this animal hospital! Their price is sky-high! Anyway, the report said that that tumor is “peripheral nerve sheath tumors”. The doctor still recommends radiation. If we decide not to do radiation, we need to monitor him closely, and as soon as the tumor grows back, a second surgical removal is required.
I google a bit about peripheral nerve sheath tumors and find that in this site, it says that,
“The pathology report says that this tumor is a schwannoma. These are also sometimes referred to as peripheral nerve sheath tumors, if you wish to search for information using that name, too. These tumors can be malignant (have the potential to spread to other areas locally or in other areas of the body). In this case, the pathologist thought that the tumor was malignant and that the malignant characteristics were strong.
The best hope for controlling the spread of these tumors when they are malignant is surgery done using strict adherence to oncological (cancer) surgical procedures. This means that a wide margin must be removed in every direction around the tumor. It sounds like your vet made an effort to do this but may not have been totally successful because there were tumor cells in the margins of the tissue submitted to the pathologist. Another possible explanation for that situation is submission of an incomplete sample. This happens when the tumor is cut into after it has been removed and made into smaller pieces so that formalin can preserve the whole thickness of the tissue submitted. Sometimes, this makes it very hard to identify the surgical margin. I think that you have to accept that the mor likely explanation is that the margin of tissue removed at the time of surgery was not enough to get all of the tumor cells.
Schwannomas do not respond well to chemotherapy, unless something very new is being used that I have not heard of, yet. The oncologist would be aware of the most research on this option. Some vets feel that these tumors respond to radiation therapy but more vets feel that they do not. I was not able to find objective information on radiation therapy, so I think that these opinions are based on a few cases and information from human research on similar tumors.
The initial surgery is usually the best chance for getting all of the tumor. However, if this tumor returns at approximately the same site, a second surgery may be beneficial. If that becomes necessary, it would be best to have a board certified surgeon or oncology surgical specialist do the second surgery, if that is possible. It takes a great deal of discipline, and faith in the technique, to remove
enough tissue around a tumor, if underlying bone or an eye have to be removed to get wide enough margins. Oncological surgeons are used to making these choices and have more experience dealing with the complications of this sort of aggressive surgical procedure.
If the oncology specialist in your area feels that radiation therapy would be helpful, it seems reasonable to me to give it a try, since other options are not available. However you do need to remember that the general feeling among oncologists appears to be that the benefits of radiation therapy are questionable for schwannomas.
Hopefully, the recover from surgery has progressed smoothly after the initial complications and there will be a long interval between this surgery and the reappearance of this tumor.
Mike Richards, DVM
12/24/2000″
What scares me is that the article says, “the general feeling among oncologists appears to be that the benefits of radiation therapy are questionable for schwannomas.” I am not sure if this statement is correct and if the technology has advanced since the post of the page. The cost is so high that I really don’t want to waste a lot of money for a questionable therapy.